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European Journal of Vascular & Endovascular Surgery 2003;25(5):432-437. The CARMEDA ® BioActive Surface is applied to a range of medical devices in our clean room. The facility includes ISO class 7 clean rooms and carefully controlled water … Ultra-smooth, flow-optimized blood contact surfaces with CARMEDA ® BioActive Surface* coating for the best possible blood compatibility Safe de-airing through de-airing port Blood pumps with tri-leaflet valves made of polyurethane and blood pumps with bileaflet valves made of carbon 2013-12-05 The effects of carmeda bioactive surface on human blood components during simulated extracorporeal circulation. J Thorac Cardiovasc Surg .
Författare. Clinical Durability of the CARMEDA BioActive Surface in EXCOR Ventricular Assist Device Pumps. Kalervo Werkkala, Janne J. Jokinen , Leena Soininen, Goran 1.0 Carmeda_chap.fm 9/10/07 12:57 pm CS0031 Produkt med Carmeda® BioActive Surface* Beskrivning Produktens blodkontaktytor är belagda med en erkända företagen inom branschen för blodkompatibla ytbeläggningar, de har bland annat utvecklat produkten Carmeda® BioActive Surface heparin coating: Carmeda Bioactive Surface, Baxter Duraflo II and a control group. Outcome was determined from a number of clinically oriented parameters, B. The lumen of the GORE® ACUSEAL Vascular Graft is coated with the CARMEDA® BioActive Surface (CBAS® Surface) consisting of a stable,. covalently Ytan som är i kontakt med blod är täckt med Carmeda® Bioactive Surface (CBAS TM)för att minska trombrisken. Eftersom pumpen är transparent är det enkel att Improvements in GORE-TEX R Vascular Graft performance by Carmeda R BioActive Surface heparin immobilization Article in European Journal of Vascular and Se Lovisa Odéns profil på LinkedIn, världens största yrkesnätverk. Lovisa har angett 11 jobb i sin profil.
The CARMEDA ® BioActive Surface is a heparin-based coating designed to actively reduce thrombus formation on blood contacting medical devices.
USP heparin sodium API of porcine origin is used in the manufacture of the Carmeda® Bioactive Surface. end-point attachment mechanism (CARMEDA® BioActive Surface (CBAS® Surface)) which serves to anchor heparin molecules to the luminal surface while still maintaining heparin’s intrinsic bioactive properties. The result is a proven thromoresistant surface with a long-term, safe clinical history. Because of its extensive publication history, there is emphasis on the CARMEDA ® BioActive Surface (CBAS ® Heparin Surface), a widely used commercialized technology for the covalent bonding of heparin.
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‡ The heparin technology of the CARMEDA® BioActive Surface is marketed as the CBAS Heparin Surface for Gore vascular devices. Material and Methods: this study investigated the utility of heparin immobilization onto expanded polytetrafluoroethylene using Carmeda® BioActive Surface technology (CBAS-ePTFE) as a means of improving vascular graft thromboresistance.
Distal cannulation sites were the left common femoral artery or the aorta below the involved segment. The cannulae were connected to a BioMedicus centrifugal pump via Carmeda bioactive surface tubings and pump heads. No systemic heparin was used. Ultra-smooth, flow-optimized blood contact surfaces with Carmeda ® BioActive Surface* coating for the best possible blood compatibility Safe de-airing through a de-airing port Valves at the inflow and outflow section guarantee that the blood flows in the right direction
Effect of Carmeda® BioActive Surface coating versus Trillium™ Biopassive Surface coating of the oxygenator on circulating platelet count drop during cardiopulmonary bypass David A Palanzo, Debra L Zarro, Norman J Manley, Ralph M Montesano, Michael Quinn, Barbara-Anne Elmore, Patricia A Gustafson, and Joseph M Castagna
Affinity CP Centrifugal Blood Pump with Carmeda® Bioactive Surface or Balance® Biosurface.
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The bioactive coating marketed by Medtronic under the name Cortiva BioActive Surface is the most researched biosurface for today's extracorporeal circulation technologies, with extensive publication of clinical and scientific evidence in peer-reviewed cardiovascular surgery, perfusion, and scientific literature. 2017-03-01 In the following experiments, we evaluated the heparin-bonded Carmeda Bioactive Surface (Medtronics Cardiopulmonary, Anaheim, Calif.) in an in vitro model of extracorporeal circulation at standard-dose heparin (5 U/ml), to examine the effects of the surface treatment on activation of blood elements, and at reduced-dose heparin (1 U/ml), to determine whether surface-bound heparin would serve as 2020-01-01 Begovac PC, Thomson RC, Fisher JL, Hughson A, Gällhagen A. Improvements in GORE-TEX® Vascular Graft performance by Carmeda® BioActive Surface heparin immobilization. European Journal of Vascular & Endovascular Surgery 2003;25(5):432-437. The CARMEDA ® BioActive Surface is applied to a range of medical devices in our clean room. The facility includes ISO class 7 clean rooms and carefully controlled water … Ultra-smooth, flow-optimized blood contact surfaces with CARMEDA ® BioActive Surface* coating for the best possible blood compatibility Safe de-airing through de-airing port Blood pumps with tri-leaflet valves made of polyurethane and blood pumps with bileaflet valves made of carbon 2013-12-05 The effects of carmeda bioactive surface on human blood components during simulated extracorporeal circulation.
CBAS abbreviation stands for Carmeda BioActive Surface. Clinical Durability of the CARMEDA BioActive Surface in EXCOR Ventricular Assist Device Pumps Kalervo Werkkala , Janne J. Jokinen , Leena Soininen, Goran Dellgren, Stefan Hallhagen, Fredrik Sundberg, Jonas Andersson, Lars I. Dahms, Nadine Jurrmann, Simon Ersel
End-point attached (EPA) heparin, using the proprietary Carmeda Bioactive Surface (CBAS Surface), was compared with other methods of covalent heparin bonding that typically yield multiple covalent linkages (using reductive amination of periodate oxidized native heparin or EDC coupling of native heparin). Biocompatible surface with bioactive binding sites for enhanced cell adhesion Synthetic polymers can provide sufficient mechanical strength in vascular graft construction, but inadequate bioactivity since lacking sufficient cellular recognition sites for cell adhesion [ 102 ].
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Textured surface (bioactive) Another bioactive surface coating is the textured surface coating. The first application of textured surface was conducted by Bernhard et al.
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Clinical Durability of the CARMEDA BioActive Surface in
Carmeda has a staff of dedicated people in a range of fields, such as Research & Development, Quality Assurance, and Manufacturing. Many of our employees are PhDs, with skills and experience in areas such as polymer & surface chemistry, biomaterials science and biocompatibility, as well as expertise in all aspects of heparin. Medtronic initiated an urgent medical device recall for 66 distributed affinity fusiontm oxygenation systems with carmeda bioactive surface due to damaged heat exchangers. product affected by this issue is limited to model cb841 sold stand alone or incorporated in total systems ts1614r1 and ts1595r7. The Carmeda BioActive Surface is a coating designed to improve blood compatibility and actively reduce thrombus formation on blood-contacting medical device surfaces. This innovative technology uses the well-established anticoagulant properties of heparin, which mimics the functional properties of the natural vessel wall.